Hi there... I found this today... I was esp. interested in the part I highlited in red where it says Causes of CRF...
~Iva~
Kidney Disease in Older Cats
By Jean Hofve, DVM
Kidney disease, in the form of chronic renal failure (CRF), is a common problem in older cats. I have seen kidney failure in cats as young as 4 years, but
far more frequently in much older cats. The most noticeable symptom is an increase in water consumption and urination ("drink-a-lot, pee-a-lot syndrome").
A blood test should be done if you notice these symptoms, as there are several conditions that can cause this. The increase in drinking and urinating in
CRF is due to loss of the kidney's ability to concentrate the urine. The kidneys have a very large reserve capacity, and symptoms of failure are not seen
until approximately 75% of kidney tissue is nonfunctional. In my experience, kidney failure is the most common cause of death in older cats.
Causes of CRF
Recent research suggests a link between vaccination for feline distemper and immune-mediated inflammation of the kidneys, which is thought to be the cause
of CRF. Annual boosters for distemper are unnecessary. Be sure to discuss all recommended vaccines with your veterinarian. A cat with kidney disease should
not be vaccinated at all.
Long-term feeding of an all-dry-food diet is also suspected as a factor in CRF. Cats' kidneys are highly efficient and adapted to life in the desert, where
they would get most or all of their water from eating their prey. Cats eating dry cat food take in only half the water that cats on a canned or homemade
diet get; this can cause stress on the kidneys over time. Dry diets also predispose cats to lower urinary tract disease (FLUTD, LUTD, FUS, crystals, stones,
cystitis) because they force such a high degree of urine concentration. Chronic or recurrent bladder disease may also be a factor in the development of
CRF.
Treating CRF
Chronic renal failure (CRF) is progressive and incurable. No conventional or alternative medical treatment can reverse its course, since the disease involves
the loss of kidney cells and replacement by scar tissue. The rate of progression in any individual cat probably cannot be slowed to any significant degree.
When the process is advanced, the kidneys become small and lumpy, and the amount of functional tissue is greatly limited. The most significant problems
caused by the loss of function are build-up of blood toxins, and anemia. These can cause weight loss, lethargy, vomiting, loss of appetite, weakness, and
other signs of illness.
Some cats are able to maintain their body weight and live relatively comfortable lives for months to years, while others succumb to the disease more quickly.
In conventional medicine, there are drugs that can minimize anemia, and phosphate binders to prevent phosphorus precipitates from further damaging the
kidneys. However, these may not be palatable, and may cause adverse reactions. They are also of little or no value unless the cat is eating a restricted
protein/low phosphorus diet exclusively. It may also be important to supplement potassium in the food. Some of the best and simplest treatments include:
Diet: The Protein Controversy
You may have heard that restricting protein is recommended for cats in kidney failure. Although this has been the "standard" treatment for decades, as far
as cats are concerned, it has always been--and remains--very controversial. According to experts at Colorado State University's veterinary teaching hospital,
restricted protein does not prevent kidney failure in a healthy cat, and has no effect on the ultimate progression of renal disease. Research also shows
that even very high protein diets do not make renal failure worse in cats (although high protein does worsen the disease in dogs and humans). The real
culprit is actually phosphorus, which meat contains in large amounts. Decreasing phosphorus intake (by restricting protein) can help some cats feel a little
better, so it may be worth a try in a symptomatic cat.
However, some studies have suggested that excessive restriction of protein may actually cause further damage to the kidneys and other organs, because there
is not enough protein for normal body maintenance and repair. Experts say that these diets are not appropriate until the BUN (Blood Urea Nitrogen) is at
least double what it should be normally (about 60-80 mg/dl).
Furthermore, there is one big problem with using the protein-restricted commercial diets: many cats don't like them, and won't eat them. Obviously, it does
little good to provide a special diet if the cat is going to starve to death! Experts emphasize that it is much more important to feed the cat what he
likes and will eat, and maintain weight and body condition, than to be overly concerned about protein content. (Please note that if you add any other protein
source to the diet, it will completely negate any possible beneficial effect from the low-phosphorus renal diet. It is useless to feed both a renal diet
and a normal protein food or meat-based treats at the same time.)
Let me say this again, because it is the single most important thing to know about CRF: feed the cat anything she will eat! IF THE CAT WON'T EAT IT, IT
WON'T HELP THE CAT! Weight loss is your cat's worst enemy in this disease; so let the cat eat what she wants!
Because water balance is so crucial, it is best to feed a high-moisture diet to help keep the cat hydrated; do not feed only dry food. Feeding mostly or
only canned food, even though it is high in phosphorus and protein, provides the moisture and calories that these cats need, in a very palatable form that
most cats will happily eat. You can also get low-phosphorus renal diets in canned form.
The best thing you can do is feed a home-prepared diet; but only if the cat will eat it! However, if the cat has never eaten homemade food, or does not
have a hearty appetite, this may not be a good time to make this switch! There are several good books on home cooking for animals, such as Dr. Pitcairn's
Guide to Natural Health for Dogs and Cats, by Richard Pitcairn, DVM, and Susan Pitcairn. (Rodale Press. ISBN 075962432.) They discuss why a diet made from
fresh, raw foods is important, and provide recipes, including a special recipe specifically designed for animals with kidney disease. Another excellent
book is Home-Prepared Dog and Cat Diets: the Healthful Alternative by Donald R. Strombeck, DVM. (Iowa State University Press. ISBN 0813821495.) If you
choose to use Dr. Strombeck's recipes, I suggest substituting 1 capsule of taurine (250 mg) for the canned clams, since clams may not contain enough taurine
for proper maintenance. For an easy starter diet, click
here.
Special Nutrition
Several nutritional supplements may be helpful for cats with kidney disease. Omega-3 fatty acids have been shown to be beneficial in CRF. Antioxidants are
also important. Both of these are contained in the highly digestible algae,
Biosuperfood.
A nutritional supplement called "Renafood" from Standard Process, is a good renal detoxifier and helps to maximize kidney function in cats. Give one or
two a day. Most cats eat them readily if they are crushed into the food. Contact
[email protected]
for more info, or call Standard Process at 1-800-558-8740 to find a distributor in your area.
Supplemental Fluids
Your veterinarian can give your cat subcutaneous fluids in the clinic, or teach you how to give them at home. This is the least intrusive and most beneficial
treatment you can give your cat. Cats in chronic renal failure drink a lot of water, but they cannot drink enough to compensate for the loss of water through
the kidneys. Subcutaneous fluids are an excellent way to help keep the toxins flushed out of the bloodstream and make the cat feel much better. If the
cat is sick or not eating, it may be necessary to hospitalize it for a few days for intravenous fluid therapy, followed by subcutaneous fluids at home
as needed. (
Click here
for detailed instructions). The recent development of a semi-permanent "port" that can be inserted in the cat's skin has taken much of the hassle out of
this procedure; talk to your vet about having this installed. It is best to have this procedure done by a veterinarian who has lots of experience with
these ports since there can be many complications.
Holistic Veterinary Care
While no treatment can create new kidney cells when scar tissue has already formed, homeopathy, herbs,
flower essences,
or acupuncture may be able to help your cat feel better and live a better quality of life. Click on this link for a directory of
holistic veterinary practitioners
by state.
Other Resources
The
Feline CRF Information Center
is an incredible website devoted to cats in renal failure. You can find out just about everything there is to know about this disease here, as well as explore
a host of excellent links to other feline health sites. You can also sign up for their email list, which can be a great resource and support for guardians
of CRF cats.
Pet Loss Support
Ultimately, fighting CRF is a losing battle, and may carry a great emotional cost to the family. Losing a beloved cat to CRF is just as traumatic as losing
a human family member, but friends and family don't always understand. There are many resources to help you through the difficult times and tough decisions
you will have to make for your cat, and to support you afterward. Many of these are listed on the Feline CRF
pet loss support
page.
For more great articles on important feline health and behavior topics, visit the Publications Page at
www.littlebigcat.com
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